
Benefits
- For bacterial or yeast skin infections.
- Clinically proven to fight bacterial and fungal skin infections.
- Helps detangle the fur and leaves the coat soft and shiny.
- Cleans and nourishes, leaving your pet’s coat soft, shiny, and lightly scented.
- Complements veterinary treatment plans and pairs well with other DOUXO® S3 PYO products for optimal results.
Composition
Active ingredients:
- Contains 3% Chlorhexidine*** & 0.5% Ophytrium®
- DOUXO® S3 range is the only pet skin care line that contains Ophytrium®, an exclusive purified natural ingredient selected for its safety and threefold action on the skin barrier.
Inactive ingredients:
- Water (Aqua)
- Cocamidopropyl Hydroxysultaine
- Decyl Glucoside
- Capryloyl Glycine
- Pentavitin® (Saccharide Isomerate)
Product Highlights
easy pump dosing; suitable for both dogs and cats.leaves fur soft, shiny, and lightly scented after each wash.
Free shipping on orders over $70
3 pcs 15% off
2 pcs 10% off
Free shipping on orders over $70
3 pcs 15% off
2 pcs 10% off
Free shipping on orders over $70
3 pcs 15% off
2 pcs 10% off
Free shipping on orders over $70
3 pcs 15% off
2 pcs 10% off
Free shipping on orders over $70
3 pcs 15% off
2 pcs 10% off
Free shipping on orders over $70
3 pcs 15% off
2 pcs 10% off
Free shipping on orders over $70
3 pcs 15% off
2 pcs 10% off
Free shipping on orders over $70
3 pcs 15% off
2 pcs 10% off
Free shipping on orders over $70
3 pcs 15% off
2 pcs 10% off
Free shipping on orders over $70
3 pcs 15% off
2 pcs 10% off
Free shipping on orders over $70
3 pcs 15% off
2 pcs 10% off
Free shipping on orders over $70
3 pcs 15% off
2 pcs 10% off
How to use
Use one pump for every 4 lbs. Double the dosage for long and/or thick fur. Wet with cool water from the neck down. First, gently massage shampoo onto the problem area. Repeat on entire body and leave on for 5-10 minutes before rinsing. Repeat if necessary. Wash hands after use. Use DOUXO®S3 PYO Mousse for a leave-on solution.
To know more about how to apply the products, watch our dedicated video:
Why Choose This Product
- Clinically proven formula – designed with veterinarians to help manage bacterial and yeast skin infections in dogs and cats.
- Dual-action care – cleanses gently while restoring and protecting the skin barrier.
Key active ingredients:
- 3% Chlorhexidine to control bacteria and yeast overgrowth.
- 0.5% Ophytrium®, a purified natural ingredient that soothes irritation, strengthens the skin barrier, and supports a healthy microbiome.
- Safe and gentle – free from soap, sulfates, parabens, colorants, phthalates, silicones, and nanoparticles. Hypoallergenic fragrance included.
- Pet-friendly design – easy-to-use pump bottle with dosing based on your pet’s weight.
- Trusted brand – part of the DOUXO® S3 line, recommended by veterinarians worldwide for effective and gentle dermatological care.
Before & After

Before Using DOUXO®
Red, irritated, or itchy skin
Excessive scratching and discomfort
Greasy or flaky coat with unpleasant odor

After Regular Use
Visibly calmer, soothed skin
Reduced itching and irritation
Soft, shiny, and fresh-smelling coat
FQA
Is DOUXO® S3 PYO Shampoo safe for both dogs and cats?
Is DOUXO® S3 PYO Shampoo safe for both dogs and cats?
Yes. The shampoo is formulated for both dogs and cats. Always follow your veterinarian’s advice for use.
How often should I bathe my pet with this shampoo?
How often should I bathe my pet with this shampoo?
Frequency depends on your pet’s skin condition and your veterinarian’s recommendation. Typically, it may be used 2–3 times per week at the start, then less often as the skin improves.
How long should I leave the shampoo on my pet’s skin?
How long should I leave the shampoo on my pet’s skin?
For best results, leave the shampoo on for 5–10 minutes before rinsing to allow active ingredients to work.
Can I use this shampoo along with other treatments or medications?
Can I use this shampoo along with other treatments or medications?
Yes, it is often used alongside other veterinary-prescribed treatments. Always consult your veterinarian before combining with other products.
Does it help with bad odors caused by skin infections?
Does it help with bad odors caused by skin infections?
Yes. By reducing bacteria and yeast on the skin, it helps eliminate unpleasant odors and leaves the coat fresh and clean.
What makes this shampoo different from regular pet shampoos?
What makes this shampoo different from regular pet shampoos?
Unlike standard shampoos, DOUXO® S3 PYO Shampoo contains 3% Chlorhexidine for antibacterial and antifungal benefits, plus Ophytrium® to support skin barrier health. It is also free from harsh chemicals.
Can it be used for long-term maintenance?
Can it be used for long-term maintenance?
Yes. Under veterinary guidance, it can be part of a long-term skin care routine to help prevent recurrence of skin issues.



